there’s youtubers that have videos about doing this in a home wetlab. very achievable. some amateur soil biologists using this to try and sample microdiversity as the planet… humanifies.
Ex-Nanopore employee here. One interesting thing we heard about internally was that OceanX[0] has one of our GridION[1] devices (slightly larger, and built-in compute) that they were using to track whales in the ocean by sequencing DNA found in seawater. Really cool.
I have a mol bio home lab, and decided against it because while the devices themselves are reasonably priced, the flow cells are an expensive disposable.
I use Plasmidsaurus instead: Pay them $15/sample online, drop off the tubes in a styrophoam box labeled with a dinosaur in a nearby university building; get the results next morning. They use Oxford Nanopore, but are loading your sample along with many other samples to maximize flow cell use.
not suprised. the website seemed to indicate to me (a layman in this area) that it expired based on time, not use- so Seqiencing As A Service (ha!) makes financial sense for most people.
i think of them as tiers of expertise— need to master the basics of structure and form before the robot has the learned representations to competently model user interactions with more fluid instantiations (by downprojecting into the overlearned fixed-semantics)
this is a pretty bad vfs. there are pure “cap manifest” approaches that don’t pull in decades of cruft semantics. don’t build systems that aren’t objectstore native in 2025 (since this work was initiated in december).
ZKML is a very exciting emerging field, but the math is no where near efficient enough to prove an inference result for an LLM yet. They are probably just trying to sell their crypto token.
there’s youtubers that have videos about doing this in a home wetlab. very achievable. some amateur soil biologists using this to try and sample microdiversity as the planet… humanifies.
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