I thought that was universal, for me it's up to Portland, down to Eugene, out to Newport (coast), over (the mountains) to Bend.
My kids, who are just starting to drive, don't know their compass directions that well (and maybe never will, thanks to GPS) so they say wrong things like "up to California".
Not a native English speaker, but living (relatively) close to the Alps, and I've definitely heard "up" meaning "towards the mountains into higher regions".
On the other hand, without thinking about it too long "out" means "to the countryside, out of town", "over" is mostly east/west and "in" is definitely the city centre.
"Down" is the odd one out, I can't pinpoint a direction.
Agree with hibbelig, I grew up in Germany (Stuttgart) and I think compass directions aren't as popular as here in the US. Maybe because all the roads are so twisty, even in the cities, that nothing goes in one direction for very long. We definitely went "down" to the city center because it was at a much lower elevation than our neighborhood.
Same in coastal Northern CA: Up the 101 to Portland, down the 101 to San Fran, over (the mountains) to Redding, or (a short drive) out to the coast.
Sometimes we’d go “up into the hills” nearby.
My kids, who are just starting to drive, don't know their compass directions that well (and maybe never will, thanks to GPS) so they say wrong things like "up to California".