Yes. Not interacting with neighbors is something that can happen naturally, but working hard to not is an entirely different thing.
Knowing your neighbors is a good thing. Even if it's just a friendly hi. You don't have to hang out, but if there's ever something you need like "did I leave the sprinkler on" or "did I leave the stove on" or "borrow a cup of sugar", it helps being on speaking terms with a neighbor rather than your first interaction with them is because you need something.
Caveat being that you live next door to Epstein or similar where not knowing them will be beneficial when the police come asking questions.