This locks up your money in the meantime, right? If so, considering the fed funds rate is 3.64% (and you can probably get higher rates on stablecoins), a huge chunk of those "winnings" is going to be eaten up by the opportunity cost of the money.
You forget that Polymarket is just a casino, and the house always wins.
For example, recent events show that any bet can be selectively disputed by arbitrary reason ("we found insiders", "we found this immoral/illegal", etc.).
If you put all your money on no, you get 4% if you win, and if Jesus comes back and you lose, money won't matter.